Llerena J M, Ruíz-Argüelles A, Alarcón-Segovia D, Llorente L, Díaz-Jouanen E
Immunology. 1981 Jun;43(2):249-54.
The same Fc gamma receptor appears to be shared for two important phenomena: antibody-dependent cellular cytotoxicity (ADCC) and antibody penetration into living cells. ADCC is inhibited through interaction with the Fc gamma receptor during the antibody penetration process, indicating that both mechanisms may modulate each other in vitro.
同一Fcγ受体似乎参与了两个重要现象:抗体依赖性细胞毒性(ADCC)和抗体穿透活细胞。在抗体穿透过程中,ADCC通过与Fcγ受体相互作用而受到抑制,这表明这两种机制在体外可能相互调节。