LyM-1基因座在小家鼠1号染色体上的位置。

Location of LyM-1 locus on Mus musculus chromosome 1.

作者信息

Sato H, Natsuume-Sakai S, Katagiri M, Itakura K

出版信息

J Immunogenet. 1981 Jun;8(3):185-9. doi: 10.1111/j.1744-313x.1981.tb00756.x.

DOI:10.1111/j.1744-313x.1981.tb00756.x

Abstract

Following segregation of the alleles at the Sas-1, LyM-1 and M1s in the (AKA/J X C3H/HeJ/F1 X C3H/HeJ backcross progeny, we found the locus responsible for the lymphocyte alloantigen LyM-1 to be closely linked to Sas-1 and M1s. The map distances are estimated to be 12.5 +/- 3.9 for Sas-1 to LyM-1, 6.9 +/- 3.0 for LyM-1 to M1s and 19.4 +/- 4.7 for Sas-1 to M1s. These data clearly indicate that the gene order is Sas-1-LyM-1-M1s on Mus musculus chromosome 1.

摘要

在（AKA/J×C3H/HeJ/F1×C3H/HeJ回交后代中，Sas-1、LyM-1和M1s的等位基因发生分离后，我们发现负责淋巴细胞同种异体抗原LyM-1的基因座与Sas-1和M1s紧密连锁。Sas-1与LyM-1之间的图距估计为12.5±3.9，LyM-1与M1s之间为6.9±3.0，Sas-1与M1s之间为19.4±4.7。这些数据清楚地表明，小家鼠1号染色体上的基因顺序是Sas-1-LyM-1-M1s。