Meyer O, Haim T
Nouv Presse Med. 1981 Jun 13;10(26):2179-84.
Thirty-five patients with systemic lupus were investigated for serum antibodies specifically directed against soluble proteic nuclear antigens similar to the SS-A and SS-B antigens. The presence of these antibodies did not make much difference in the clinical and biological symptoms of the disease, except for a higher incidence of Gougerot-Sjögren's syndrome with clinical manifestations. Their prevalence in systemic lupus erythematosus was 35%, anti-SS-A antibodies being more frequent than anti-SS-B antibodies (27% and 4,5% respectively). A third different antibody was found in 3% of the patients. These precipitating anti-SS-A or SS-B antibodies have no prognostic significance. They may be present in the absence of antinuclear antibodies detectable by immunofluorescence.
对35例系统性红斑狼疮患者进行了研究，以检测其血清中是否存在特异性针对类似于SS - A和SS - B抗原的可溶性蛋白质核抗原的抗体。这些抗体的存在对该疾病的临床和生物学症状影响不大，只是伴有临床表现的古热洛 - 舍格伦综合征的发病率较高。它们在系统性红斑狼疮中的患病率为35%，抗SS - A抗体比抗SS - B抗体更常见（分别为27%和4.5%）。在3%的患者中发现了第三种不同的抗体。这些沉淀性抗SS - A或抗SS - B抗体没有预后意义。它们可能在免疫荧光检测不到抗核抗体的情况下存在。
