Cameron J L, Gayler B W, Zuidema G D
Ann Surg. 1978 Oct;188(4):552-61. doi: 10.1097/00000658-197810000-00012.
Between 1969 and 1978, 45 patients with biliary strictures have been managed surgically utilizing silastic transhepatic stents. In 25 patients the strictures were benign. After resection or dilatation of the benign stricture, an hepaticojejunostomy was performed to a Roux-en-Y loop. The anastomosis was stented with a large bore silastic tube with multiple side holes passed through the biliary tree, out the anterior surface of the liver, and then out through the abdominal wall. There was one hospital death. Most stents were left in place for one year. Of the 15 patients with long-term follow-up, all have had excellent results. In 20 patients the strictures were malignant and involved the common hepatic duct in 10 patients or its bifuraction in 10 patients. In 14 patients the tumor was thought to be primary in the biliary tree, and in six patients the tumor was felt to represent a metastasis or direct extension from another site. In three patients the tumors were resected, and in the remaining they were dilated or bypassed. After positioning a silastic transhepatic stent, a hepaticojejunostomy was carried out. There were two hospital deaths. Serum bilirubin on admission average 17.1 mg%, and after decompression 1.8 mg%. Five patients have survived over one year, and two over two years. Postoperative radiotherapy and a primary biliary tumor favored longer survival.
1969年至1978年间,45例胆管狭窄患者接受了使用硅橡胶经肝支架的手术治疗。其中25例患者的狭窄为良性。在切除或扩张良性狭窄后,进行肝空肠吻合术,吻合至Roux-en-Y袢。吻合口用一根大口径、带有多个侧孔的硅橡胶管支撑,该管穿过胆管树,从肝脏前表面穿出,然后穿出腹壁。有1例医院死亡病例。大多数支架留置一年。在15例接受长期随访的患者中,所有患者效果良好。20例患者的狭窄为恶性,其中10例累及肝总管,10例累及肝门分叉处。14例患者的肿瘤被认为起源于胆管树,6例患者的肿瘤被认为是其他部位的转移瘤或直接蔓延所致。3例患者的肿瘤被切除,其余患者的肿瘤进行了扩张或旁路手术。放置硅橡胶经肝支架后,进行肝空肠吻合术。有2例医院死亡病例。入院时血清胆红素平均为17.1mg%,减压后为1.8mg%。5例患者存活超过一年,2例存活超过两年。术后放疗和原发性胆管肿瘤有利于延长生存期。