Tuomilehto J, Puska P, Tanskanen A, Karppanen H, Pietinen P, Nissinen A, Enlund H, Ruotsalainen P
Acta Cardiol. 1981;36(2):83-104.
A community-based programme to reduce salt consumption to lower general blood pressure levels has been started in North Karelia, a county eastern Finland with high hypertension and CVD rates. The programme is based on the previous activity in the community to control CVD risk factors (the North Karelia Project). Previously, however, salt reduction was not included among the objectives. The aim of the study is to evaluate the feasibility and effects of this new community programme to reduce salt intake. The study period is from spring 1979 to spring 1982. At the outset and at the end cross-sectional random population samples, ages 14 to 65, are examined both in North Karelia and a matched reference community. The surveys include among other measurements 24-hour urine collection (for Na, K and creatinine excretion) and blood pressure. The effect evaluation is concerned whether the programme reduced the general salt intake and whether this was associated with reduction in blood pressure levels among the population. Principles and methods of intervention are presented. Preliminary results from the baseline survey confirmed the high salt intake of the population: the mean 24-hour urinary Na excretion was 215-218 mmol among men and 171-173 mmol among women. The respective K excretion values were 89-91 mmol and 72-72 mmol, and Na/K ratios 2.5-2.6 and 2.4-2.5.
在芬兰东部一个高血压和心血管疾病发病率较高的省份北卡累利阿,已经启动了一项以社区为基础的项目,旨在减少盐的摄入量,以降低总体血压水平。该项目基于此前社区控制心血管疾病风险因素的活动(北卡累利阿项目)。然而,此前盐的减少并未被纳入目标之中。本研究的目的是评估这个新的社区项目减少盐摄入量的可行性和效果。研究期从1979年春季至1982年春季。在开始和结束时,对北卡累利阿和一个匹配的对照社区中14至65岁的横断面随机人群样本进行检查。调查包括24小时尿液收集(用于检测钠、钾和肌酐排泄)以及血压测量等项目。效果评估关注该项目是否降低了总体盐摄入量,以及这是否与人群血压水平的降低相关。文中介绍了干预的原则和方法。基线调查的初步结果证实了该人群盐摄入量较高:男性24小时尿钠排泄平均值为215 - 218毫摩尔,女性为171 - 173毫摩尔。相应的钾排泄值分别为89 - 91毫摩尔和72 - 72毫摩尔,钠/钾比值分别为2.5 - 2.6和2.4 - 2.5。