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Bull World Health Organ. 1980;58(5):753-6.
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Demand for nonhuman primate resources in the age of biodefense.生物防御时代对非人灵长类动物资源的需求。
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本文引用的文献

1
The immune response of the guinea pig to the antigens of Pasteurella pestis.豚鼠对鼠疫杆菌抗原的免疫反应。
J Immunol. 1958 Feb;80(2):132-41.
2
Virulence in Pasteurella pestis.鼠疫耶尔森菌的毒力
Science. 1954 Mar 26;119(3091):413-4. doi: 10.1126/science.119.3091.413.
3
Freeze-drying various attenuated strains of Pasteurella pestis.
Cryobiology. 1970 Jul-Aug;7(1):40-3. doi: 10.1016/0011-2240(70)90043-x.
4
Effectiveness of live or killed plague vaccines in man.活疫菌或死疫菌鼠疫疫苗对人类的有效性。
Bull World Health Organ. 1970;42(5):653-66.
5
Plague immunization. V. Indirect evidence for the efficacy of plague vaccine.鼠疫免疫。五、鼠疫疫苗效力的间接证据。
J Infect Dis. 1974 May;129:Suppl:S37-40. doi: 10.1093/infdis/129.supplement_1.s37.
6
Measuring the efficacy of vaccination in affording protection against plague.衡量疫苗接种在提供鼠疫防护方面的效力。
Bull World Health Organ. 1979;57(2):309-13.

由无毒力的鼠疫耶尔森氏菌制备的灭活鼠疫疫苗的效力。

Potency of killed plague vaccines prepared from avirulent Yersinia pestis.

作者信息

Williams J E, Altieri P L, Berman S, Lowenthal J P, Cavanaugh D C

出版信息

Bull World Health Organ. 1980;58(5):753-6.

PMID:6975184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2395990/
Abstract

Killed plague vaccines prepared from avirulent strains A1122 and EV76S of Yersinia pestis were more effective in mouse potency tests than samples of Plague Vaccine, USP, prepared from killed Y. pestis of the virulent strain 195/P. Manufacture of vaccine from avirulent Y. pestis would obviate requirements for the large containment facilities that are currently needed for producing Plague Vaccine, USP.

摘要

用鼠疫耶尔森氏菌无毒株A1122和EV76S制备的灭活鼠疫疫苗，在小鼠效力试验中比用强毒株195/P的灭活鼠疫耶尔森氏菌制备的美国药典鼠疫疫苗样本更有效。用无毒鼠疫耶尔森氏菌生产疫苗将无需目前生产美国药典鼠疫疫苗所需的大型防护设施。