Connolly J F
Clin Orthop Relat Res. 1981 Nov-Dec(161):39-53.
Management of nonunions requires careful and critical assessment of the true biologic status of the fracture. The mere radiographic persistence of a fracture line does not invariably indicate nonunion. Ten percent of fractures considered initially to be ununited in this series healed spontaneously without further treatment. The patient who has no pain with weight-bearing and no demonstrable motion on careful stress studies does not usually require further treatment, except for protection against reinjury. Intraosseous venography may be useful to distinguish the delayed from the nonunion in order to institute appropriate and early treatment. Percutaneous direct-current electrostimulation is proving to be a reliable and effective method of managing the most common nonunion of the tibia or distal femur. It appears less satisfactory for the more proximal femoral fractures and for fractures of the humerus. Electrical stimulation does not eliminate the need to stabilize the nonunion of either the femur or the upper limb. Electrical stimulation also does not eliminate the need for bone grafting in approximately 15% to 20% of nonunions. The fractures' biologic inability to respond may be identifiable by 99MTc diphosphonate bone scan. The implantable direct-current electrical stimulatory device proved ineffective in this series. Hopefully, further development of this technology may produce more consistent results in the future. The electromagnetic noninvasive stimulator appears to be a useful alternative method to the semi-invasive system. This, of course, should depend on the individual needs of the patient and the nature and location of the fracture. Continued technologic improvement in all electrical stimulatory methods should broaden their usefulness and applicability. However, the healing status of the fracture and the processes by which each fracture responds must be carefully assessed to appreciate what is being effected by electrical stimulation. Critical evaluation and clarification of indications are essential if the patient is to be offered the most effective therapy available.
骨不连的治疗需要对骨折的真实生物学状态进行仔细且严格的评估。仅仅骨折线在影像学上持续存在并不一定意味着骨不连。在本系列中,最初被认为是骨不连的骨折中有10%未经进一步治疗而自行愈合。负重时无疼痛且在仔细的应力研究中无明显活动的患者通常无需进一步治疗,除非防止再次受伤。骨内静脉造影可能有助于区分延迟愈合与骨不连,以便进行适当且早期的治疗。经皮直流电刺激已被证明是治疗胫骨或股骨远端最常见骨不连的一种可靠且有效的方法。对于股骨近端骨折和肱骨骨折,其效果似乎不太理想。电刺激并不能消除稳定股骨或上肢骨不连的必要性。在大约15%至20%的骨不连病例中,电刺激也不能消除骨移植的必要性。骨折在生物学上无反应的情况可通过99MTc二膦酸盐骨扫描来识别。在本系列中,可植入式直流电刺激装置被证明无效。希望该技术的进一步发展在未来能产生更一致的结果。电磁无创刺激器似乎是半侵入性系统的一种有用替代方法。当然,这应取决于患者的个体需求以及骨折的性质和部位。所有电刺激方法在技术上的持续改进应能拓宽其用途和适用性。然而,必须仔细评估骨折的愈合状态以及每个骨折的反应过程,以了解电刺激所产生的效果。如果要为患者提供最有效的治疗,对适应证进行严格评估和明确至关重要。