同基因胸腺碎片、胸腺上皮和胸腺细胞移植对成年去胸腺小鼠接触敏感性反应增强的抑制作用。
Inhibitory effect of transplanted syngeneic thymus fragments, thymus epithelium and thymocytes on the increased contact sensitivity reaction in the adult thymectomized mouse.
作者信息
Olafsson J H, Lindholm L, Roupe G
出版信息
Int Arch Allergy Appl Immunol. 1982;67(1):93-5. doi: 10.1159/000232994.
PMID:6976941
Abstract
Thymectomy in the adult mouse leads to an increased ability to develop contact sensitivity. The effect of different types of thymus grafts to adult thymectomized mice on contact sensitivity was studied in the present investigation. An inhibition was observed after transplantation either of uncultured thymus tissue, cultured thymus epithelium or of thymocytes. The results of the study favor the hypothesis that a continuous production of suppressor cells regulates contact sensitivity in the adult mouse.
摘要
成年小鼠胸腺切除术后，其产生接触敏感性的能力增强。本研究探讨了不同类型的胸腺移植对成年胸腺切除小鼠接触敏感性的影响。移植未培养的胸腺组织、培养的胸腺上皮或胸腺细胞后均观察到抑制作用。该研究结果支持以下假说：成年小鼠中抑制性细胞的持续产生调节接触敏感性。
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Inhibitory effect of transplanted syngeneic thymus fragments, thymus epithelium and thymocytes on the increased contact sensitivity reaction in the adult thymectomized mouse.同基因胸腺碎片、胸腺上皮和胸腺细胞移植对成年去胸腺小鼠接触敏感性反应增强的抑制作用。
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