Pelc S, Fondu P, Otten J, Gompel C
Acta Neuropathol. 1981;55(4):289-92. doi: 10.1007/BF00690992.
In a patient with systemic and nervous system IBS, the CSF cells were investigated by light and electron microscopy. An IBS of the B-cell type was identified in the CSF which proved, at both morphological levels, to be identical to that recorded in IBS in lymphoid tissue with regard to the malignant cell types and the absence of surface specialization. In contrast, unusual macrophages were observed in the CSF instead of the reticular elements associated with IBS in lymph nodes which present desmosomes. They demonstrated both phagocytosis and emperipolesis and also displayed autodesmosomes. The CSF phagocytes are discussed in relationship with the phagocytes described in the brain with malignant lymphoma.
在一名患有全身性和神经系统原发性中枢神经系统淋巴瘤（IBS）的患者中，通过光学显微镜和电子显微镜对脑脊液细胞进行了研究。在脑脊液中鉴定出B细胞型IBS，在形态学层面上，其恶性细胞类型以及缺乏表面特化现象均与淋巴组织中的IBS记录情况相同。相比之下，在脑脊液中观察到的是异常巨噬细胞，而非淋巴结中与具有桥粒的IBS相关的网状成分。它们表现出吞噬作用和血细胞渗出，并且还显示出自桥粒。本文讨论了脑脊液吞噬细胞与脑内恶性淋巴瘤中所描述的吞噬细胞之间的关系。
