小牛高迁移率族非组蛋白染色体蛋白的组织特异性研究。
Studies on the tissue specificity of the high-mobility-group non-histone chromosomal proteins from calf.
作者信息
Rabbani A, Goodwin G H, Johns E W
出版信息
Biochem J. 1978 Aug 1;173(2):497-505. doi: 10.1042/bj1730497.
Abstract
The high-mobility-group (HMG) non-histone chromosomal proteins from calf thymus, liver, spleen and kidney were extracted, and fractionated by CM-Sephadex chromatography and trichloroacetic acid precipitation. The isolated proteins HMG 1, HMG 2 and HMG 17 from the tissues were compared by polyacrylamide-gel electrophoresis, isoelectric focusing and amino acid analysis. The results show that the three proteins are very similar in the tissues studied, implying a lack of tissue specificity.
摘要
从小牛胸腺、肝脏、脾脏和肾脏中提取高迁移率族（HMG）非组蛋白染色体蛋白，并通过CM-葡聚糖凝胶色谱法和三氯乙酸沉淀法进行分级分离。通过聚丙烯酰胺凝胶电泳、等电聚焦和氨基酸分析对从这些组织中分离出的蛋白HMG 1、HMG 2和HMG 17进行比较。结果表明，在所研究的组织中这三种蛋白非常相似，这意味着缺乏组织特异性。
Zotero 插件