Dijkmans B A, van Hooff J P, de Wolff F A, Mattie H
Br J Clin Pharmacol. 1981 Nov;12(5):701-3. doi: 10.1111/j.1365-2125.1981.tb01293.x.
1 Co-trimoxazole induces a highly significant and reversible elevation of the serum creatinine level. 2 In renal-allograft patients the degree of this elevation is significantly correlated with the concentration of serum creatinine before administration of co-trimoxazole and with the concentration of non-protein-bound trimethoprim.