患者血清与商业质量控制血清的方法间分析变异性比较。

Comparison of intermethod analytical variability of patient sera and commercial quality control sera.

作者信息

van Helden W C, Visser R W, Van den Bergh F A, Souverijn J H

出版信息

Clin Chim Acta. 1979 May 2;93(3):335-47. doi: 10.1016/0009-8981(79)90283-3.

Abstract

The intermethod analytical variability of 59 commercially available control sera was compared with that of patient sera. For this purpose, patient and control sera were assayed with respect to ten constituents (albumin, alkaline phosphatase, alpha-amylase, cholesterol, glucose, iron, lactate dehydrogenase, creatinine, protein, and urea), each with two analytical methods. Only 6 of the 59 control materials showed an intermethod analytical variability comparable to that of the patient sera for all of the determinations. The use of patient sera for the calibration of routine analytical methods is recommended.

摘要

将59种市售对照血清的方法间分析变异性与患者血清的进行了比较。为此，对患者血清和对照血清的十种成分（白蛋白、碱性磷酸酶、α淀粉酶、胆固醇、葡萄糖、铁、乳酸脱氢酶、肌酐、蛋白质和尿素）进行了检测，每种成分采用两种分析方法。在所有测定中，59种对照材料中只有6种显示出与患者血清相当的方法间分析变异性。建议使用患者血清来校准常规分析方法。