Hay R J, Shennan G
Br J Dermatol. 1982 Feb;106(2):191-8. doi: 10.1111/j.1365-2133.1982.tb00928.x.
In patients infected with Trichophyton rubrum, the T lymphocyte responses (lymphocyte transformation) to trichophytin were reduced, compared with control subjects. The same levels were seen in patients with intractable chronic infection and those who responded well to treatment but the site of infection affected the immune response, lower levels being seen in patients with palmo-plantar infection than in those with groin infections. In infections coursed by T. mentagrophytes by contrast, lymphocyte responses to specific antigens were significantly increased.
与对照受试者相比，感染红色毛癣菌的患者对癣菌素的T淋巴细胞反应（淋巴细胞转化）降低。在患有顽固性慢性感染的患者以及对治疗反应良好的患者中也观察到相同水平，但感染部位会影响免疫反应，掌跖感染患者的水平低于腹股沟感染患者。相比之下，在须癣毛癣菌引起的感染中，淋巴细胞对特定抗原的反应显著增加。
