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左旋多巴预处理前后进行自行车测力计运动时的血浆睾酮水平。

Plasma testosterone during bicycle ergometer exercise without and after L-dopa pretreatment.

作者信息

Jezová-Repceková D, Vigas M, Mikulaj L, Jurcovicová J

出版信息

Endocrinol Exp. 1982 Mar;16(1):3-8.

PMID:6978249
Abstract

The level of testosterone in plasma during submaximal, prolonged submaximal and maximal exercise on a bicycle ergometer was measured in healthy untrained men. To evaluate the possible involvement of prolactin in the regulation of testosterone secretion during exercise, the influence of prolactin inhibition by oral L-dopa (1 g) pretreatment was also studied. The exercise evoked a small but significant rise of testosterone concentration with peak levels immediately at the end of work performance or 10 min after that. No substantial difference between the response to submaximal and maximal exercise was noted. In these experiments the findings by others on a lack of plasma LH changes and significant increase of plasma prolactin were confirmed. Pharmacological blockade of prolactin release by L-dopa pretreatment failed to modify the response of testosterone to bicycle ergometer exercise. It may be suggested that prolactin is not involved in the induction of plasma testosterone increase during physical exercise.

摘要

对健康的未经训练的男性,测量了他们在自行车测力计上进行次最大强度、长时间次最大强度和最大强度运动期间血浆睾酮水平。为了评估催乳素在运动期间睾酮分泌调节中可能的作用,还研究了口服左旋多巴(1克)预处理抑制催乳素的影响。运动引起睾酮浓度小幅但显著升高,峰值水平在工作结束时或结束后10分钟立即出现。次最大强度运动和最大强度运动的反应之间未观察到实质性差异。在这些实验中,证实了其他人关于血浆促黄体生成素(LH)无变化以及血浆催乳素显著增加的发现。左旋多巴预处理对催乳素释放的药理阻断未能改变睾酮对自行车测力计运动的反应。可以认为,催乳素不参与体育锻炼期间血浆睾酮增加的诱导过程。

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Plasma testosterone during bicycle ergometer exercise without and after L-dopa pretreatment.左旋多巴预处理前后进行自行车测力计运动时的血浆睾酮水平。
Endocrinol Exp. 1982 Mar;16(1):3-8.
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