Leung F W, Drenick E J, Stanley T M
Am J Gastroenterol. 1982 Feb;77(2):67-72.
We have examined complications involving the defunctionalized bowel in 119 intestinal bypass patients. In this group, we found a 66% of incidence of bypass enteropathy. Pneumatosis cystoides intestinalis was present in three patients, severe blood loss in three, localized ulcerations in two, intermittent or chronic intussusception of the proximal jejunal stump in 10, and extensive stenosis relating to tight fibrous adhesions in one patient. The stenosis may become manifest as an obstructive process only after reconstitution of normal bowel continuity. Bacterial overgrowth in the bypassed small bowel was the primary cause for most of the lesions. A consistent diagnostic finding, suggesting disease in the excluded bowel, was ileal distention and the presence of gas-fluid levels on upright abdominal x-rays. Definitive diagnoses of ulceration, intussusception, and/or obstruction were sometimes possible only during laparotomy. Because the bypassed bowel cannot be examined with conventional techniques, these various abnormalities must be suspected when ill-defined abdominal complaints are observed in bypass patients. Metronidazole, to suppress anaerobic organisms, or suitable broad spectrum antibiotics can relieve the various lesions of the inflammatory process, whereas appropriate surgical procedures may be required for some of the chronic or recurrent complications.
我们对119例接受肠道旁路手术的患者中涉及失功能肠段的并发症进行了研究。在这组患者中,我们发现旁路性肠病的发生率为66%。3例患者出现肠壁囊样积气,3例严重失血,2例局部溃疡,10例近端空肠残端出现间歇性或慢性肠套叠,1例患者因紧密纤维粘连出现广泛狭窄。这种狭窄可能只有在恢复正常肠道连续性后才会表现为梗阻性病变。旁路小肠内细菌过度生长是大多数病变的主要原因。一个提示被旷置肠段病变的一致诊断性发现是回肠扩张以及立位腹部X线片上出现气液平面。溃疡、肠套叠和/或梗阻的明确诊断有时仅在剖腹手术时才能做出。由于无法用传统技术检查被旷置的肠段,当旁路手术患者出现不明原因的腹部不适时,必须怀疑存在这些各种异常情况。甲硝唑用于抑制厌氧菌,或使用合适的广谱抗生素可缓解炎症过程中的各种病变,而对于一些慢性或复发性并发症可能需要采取适当的手术治疗。