Hedberg S E, Fowler D L, Ryan R L
Am J Surg. 1982 Apr;143(4):426-31. doi: 10.1016/0002-9610(82)90191-x.
Fifty-three patients with upper gastrointestinal bleeding and proven esophageal varices were treated by intravascular injection sclerotherapy of the varices using a mixture of ethanolamine oleate, bovine thrombin and cephalothin. An intraesophageal balloon was used to impede craniad flow during the injection. Except in three patients who failed to stop bleeding from nonvariceal lesions, sclerotherapy was 94 percent successful in controlling bleeding. The mortality rate in sclerotherapy patients with ascites was 25 percent compared with 54 to 75% reported elsewhere. There has been no rebleeding from varices after the third treatment week in patients followed up for up to 14 months.
53例确诊为食管静脉曲张且出现上消化道出血的患者，接受了使用油酸乙醇胺、牛凝血酶和头孢噻吩混合液对静脉曲张进行血管内注射硬化疗法的治疗。注射过程中使用食管内气囊来阻止血液向头端流动。除3例因非静脉曲张性病变出血未能止血外，硬化疗法控制出血的成功率为94%。有腹水的硬化疗法患者死亡率为25%，而其他地方报道的死亡率为54%至75%。随访长达14个月的患者在第三次治疗周后未再出现静脉曲张出血。
