替卡西林生物测定法。
Ticarcillin bioassay.
作者信息
Bannatyne R M, Cheung R
出版信息
Antimicrob Agents Chemother. 1981 Oct;20(4):493-5. doi: 10.1128/AAC.20.4.493.
Abstract
An accurate, plate diffusion bioassay for ticarcillin, utilizing the fast-replicating Beneckea natriegens and 4% salt agar, is described in this report. Zones of inhibition were well defined after 3 h, and the limit of sensitivity was around 5.0 mug/ml. The assay is simple to carry out, and duplicate assays can be performed on as little as 40 mul of serum.
摘要
本报告介绍了一种利用快速繁殖的纳氏贝内克氏菌和4%盐琼脂对替卡西林进行准确的平板扩散生物测定法。3小时后抑菌圈清晰可见，灵敏度极限约为5.0微克/毫升。该测定法操作简单，仅用40微升血清即可进行重复测定。
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本文引用的文献
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Pseudomonas natriegens, a marine bacterium with a generation time of less than 10 minutes.嗜盐栖热假单胞菌，一种世代时间少于10分钟的海洋细菌。
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Clinical pharmacology of ticarcillin in the newborn infant: relation to age, gestational age, and weight.
J Pediatr. 1975 Sep;87(3):474-9. doi: 10.1016/s0022-3476(75)80664-0.
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Gentamicin and ticarcillin serum levels.
JAMA. 1979 Jun 1;241(22):2401-3.
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Antibacterial activity of ticarcillin, tobramycin and gentamicin alone and in combination against Pseudomonas aeruginosa in vitro.替卡西林、妥布霉素和庆大霉素单独及联合应用对铜绿假单胞菌的体外抗菌活性。
Chemotherapy. 1977;23(5):314-23. doi: 10.1159/000222001.
9
Synergy between ticarcillin and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae in vitro and in vivo.替卡西林与妥布霉素对铜绿假单胞菌和肠杆菌科细菌的体外及体内协同作用。
Antimicrob Agents Chemother. 1977 Jun;11(6):956-64. doi: 10.1128/AAC.11.6.956.
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Chloramphenicol bioassay.氯霉素生物测定法。
Antimicrob Agents Chemother. 1979 Jul;16(1):43-5. doi: 10.1128/AAC.16.1.43.
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