氯霉素生物测定法。
Chloramphenicol bioassay.
作者信息
Bannatyne R M, Cheung R
出版信息
Antimicrob Agents Chemother. 1979 Jul;16(1):43-5. doi: 10.1128/AAC.16.1.43.
Abstract
An accurate plate diffusion bioassay for chloramphenicol is described, in which the fast-replicating Beneckea natriegens and 1.5% salt agar are used. Zones of inhibition were well defined after 3 h, and the limit of sensitivity of the method was around 2 mug/ml. The concurrent presence of gentamicin did not influence the assay. The assay is simple to carry out and duplicate assays can be performed with as little as 100 mug of capillary blood.
摘要
本文描述了一种用于氯霉素的准确的平板扩散生物测定法，该方法使用快速复制的纳氏贝内克氏菌和1.5%的盐琼脂。3小时后抑菌圈清晰可辨，该方法的灵敏度极限约为2微克/毫升。庆大霉素的同时存在不影响测定。该测定法易于实施，仅用100微克毛细血管血即可进行重复测定。
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DIFFUSION PLATE ASSAY FOR CHLORAMPHENICOL AND AUREOMYCIN.氯霉素和金霉素的扩散平板测定法
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High-performance liquid chromatographic assay of chloramphenicol in serum.血清中氯霉素的高效液相色谱测定法
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Determination of chloramphenicol in serum and cerebrospinal fluid with high-pressure liquid chromatography.
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Simplified radioenzymatic assay for chloramphenicol.氯霉素简易放射酶测定法
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