Smith H C, Hammes L N, Gupta S, Vlietstra R E, Elveback L
Circulation. 1982 Jun;65(7 Pt 2):120-5. doi: 10.1161/01.cir.65.7.120.
Factors that influence the effect of coronary artery bypass graft surgery (CABG) on employment were examined in 1427 2-year survivors from entry into the nonrandomized Mayo Clinic portion of the National Heart, Lung, and Blood Institute's prospective Coronary Artery Surgery Study. Five hundred seventy-nine patients (41%) were treated medically, 769 (54%) were treated surgically and 79 (5%) were initially treated medically but later had CABG. All groups were similar at entry with respect to age and percent working, retired or quitting work for cardiac reasons. There was a similar decline in employment from entry to 2 years in all three groups. The number who quit work for cardiac reasons was twice the number of previously disabled workers who returned to work with all three modes of therapy. Univariate and multivariate analyses were used to test the independent prognostic values of a number of variables for subsequent employment in the largest homogeneous surgical subset--496 nonretired males. Postoperative angina was the most powerful factor reducing postoperative employment. Postoperative employment was also lower if the patient was not working before surgery, was a laborer, or older than age 55 years (all p less than 0.01). Although the level of nonwork physical activity was generally increased after CABG, there was no relationship between physical activity and employment. This study confirms that employment declines after CABG, but three of the four most powerful prognostic variables were not related to surgery.
在国家心肺血液研究所前瞻性冠状动脉手术研究中,从进入非随机的梅奥诊所部分的1427名2年幸存者中,研究了影响冠状动脉搭桥手术(CABG)对就业影响的因素。579名患者(41%)接受药物治疗,769名(54%)接受手术治疗,79名(5%)最初接受药物治疗但后来接受了冠状动脉搭桥手术。所有组在入组时年龄和工作、退休或因心脏原因停止工作的比例方面相似。所有三组从入组到2年的就业情况都有类似下降。因心脏原因停止工作的人数是之前残疾但通过所有三种治疗方式恢复工作的工人人数的两倍。单因素和多因素分析用于检验在最大的同质手术亚组——496名未退休男性中,一些变量对后续就业的独立预后价值。术后心绞痛是降低术后就业的最有力因素。如果患者术前未工作、是体力劳动者或年龄超过55岁,术后就业情况也较低(所有p均小于0.01)。虽然冠状动脉搭桥手术后非工作身体活动水平总体上有所提高,但身体活动与就业之间没有关系。这项研究证实冠状动脉搭桥手术后就业情况会下降,但四个最有力的预后变量中有三个与手术无关。