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同期心肌血运重建术和颈动脉内膜切除术。

Simultaneous myocardial revascularization and carotid endarterectomy.

作者信息

Schwartz R L, Garrett J R, Karp R B, Kouchoukos N T

出版信息

Circulation. 1982 Aug;66(2 Pt 2):I97-101.

PMID:6979441
Abstract

Two methods for performing simultaneous carotid endarterectomy and coronary artery bypass grafting (CABG) were compared in 73 patients. A technique for performing carotid endarterectomy during cardiopulmonary bypass providing hypothermic cerebral protection was used in 37 patients (group 1). The 36 other patients (group 2) underwent carotid endarterectomy immediately before cardiopulmonary bypass was instituted. The mean age, New York Heart Association functional class, ventricular function and extent of carotid disease were similar in the two groups. The proportion of patients with previous myocardial infarction or stroke was higher in group 1 (p less than 0.05). One permanent neurologic deficit (technical error) and one transient neurologic deficit occurred in group 1 and none in group 2 (NS). Twenty-seven patients (37%) had left main disease, compared with an institutional incidence of 14.2% for all coronary operations. Five of seven patients who died early (three in group 1 and four in group 2) had left main disease. No advantage of one method over the other could be demonstrated. Patients with left main coronary artery disease and carotid disease have an increased operative risk.

摘要

对73例患者比较了两种同期行颈动脉内膜切除术和冠状动脉旁路移植术(CABG)的方法。37例患者(第1组)采用在体外循环期间进行颈动脉内膜切除术并提供低温脑保护的技术。另外36例患者(第2组)在建立体外循环之前立即进行颈动脉内膜切除术。两组患者的平均年龄、纽约心脏协会心功能分级、心室功能和颈动脉疾病程度相似。第1组既往有心肌梗死或卒中的患者比例较高(p<0.05)。第1组发生1例永久性神经功能缺损(技术失误)和1例短暂性神经功能缺损,第2组无神经功能缺损发生(无显著性差异)。27例患者(37%)有左主干病变,而所有冠状动脉手术的机构发生率为14.2%。7例早期死亡患者中有5例(第1组3例,第2组4例)有左主干病变。未显示一种方法优于另一种方法。左主干冠状动脉疾病和颈动脉疾病患者的手术风险增加。

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