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冠状动脉疾病合并颈动脉疾病的手术策略

Operative strategy in combined coronary and carotid artery disease.

作者信息

Minami K, Sagoo K S, Breymann T, Fassbender D, Schwerdt M, Körfer R

机构信息

Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine-Westphalia, Bad Oeynhausen, Federal Republic of Germany.

出版信息

J Thorac Cardiovasc Surg. 1988 Feb;95(2):303-9.

PMID:3339897
Abstract

In the period between the opening of our heart center in November 1984 and May 1986, 2001 cardiac operations were performed with the aid of cardiopulmonary bypass. Almost three quarters (73.5%, n = 1471) of the patients had coronary artery disease and 20% (n = 359) had acquired valvular heart disease. In 47 of 1471 patients who underwent coronary artery bypass grafting, a simultaneous carotid endarterectomy was performed. They included 36 men and 11 women, aged between 51 and 78 years (mean 64 years). Preoperatively, 12 patients had cerebrovascular symptoms and 35 were neurologically asymptomatic. Twenty-three had unilateral carotid stenosis and 24 had bilateral or multiple vessel disease of the extracranial arteries. All except four patients had triple-vessel coronary artery disease. In three patients with aortic valve disease, coronary bypass, carotid endarterectomy, and aortic valve replacement were performed simultaneously. Cardiopulmonary bypass was instituted before carotid endarterectomy was performed, with mild hypothermia and hemodilution for added protection. Electroencephalographic monitoring was used throughout the operation. Forty-six of the 47 patients survived the operation without neurologic or cardiac complications. One patient had a neurologic deficit with hemiplegia and coma, which was lethal. We conclude that simultaneous endarterectomy of significant extracranial artery stenosis in candidates for coronary bypass is a method safe enough to justify its routine use.

摘要

在我们心脏中心于1984年11月开业至1986年5月期间,借助体外循环进行了2001例心脏手术。几乎四分之三(73.5%,n = 1471)的患者患有冠状动脉疾病,20%(n = 359)患有后天性心脏瓣膜病。在1471例行冠状动脉旁路移植术的患者中,有47例同时进行了颈动脉内膜切除术。其中包括36名男性和11名女性,年龄在51岁至78岁之间(平均64岁)。术前,12例患者有脑血管症状,35例无神经方面症状。23例有单侧颈动脉狭窄,24例有双侧或多支颅外动脉疾病。除4例患者外,所有患者均患有三支血管冠状动脉疾病。在3例患有主动脉瓣疾病的患者中,同时进行了冠状动脉旁路移植术、颈动脉内膜切除术和主动脉瓣置换术。在进行颈动脉内膜切除术之前建立体外循环,采用轻度低温和血液稀释以加强保护。整个手术过程中使用脑电图监测。47例患者中有46例术后存活,无神经或心脏并发症。1例患者出现偏瘫和昏迷的神经功能缺损,最终死亡。我们得出结论,对于冠状动脉旁路移植术候选患者同时进行严重颅外动脉狭窄的内膜切除术是一种足够安全的方法,值得常规使用。

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