Razaboni R M, Greco M A, Harper A D, Shaw W W, Ballantyne D L
J Microsurg. 1981 Winter;3(2):65-71. doi: 10.1002/micr.1920030202.
Segments 15 mm in length were excised from the femoral veins of rats and preserved by refrigeration at 4 C in lactated Ringer's solution for periods up to 21 days. The findings show that veins can be preserved for up to seven days and successfully grafted to recipients. Although there was some success in preserving vein segments for more than seven days, a high rate of thrombosis occurred after implantation in the recipients. It is generally accepted that damaged endothelium causes thrombosis. The light and electron microscopic observations in this study, however, suggest that the condition of the endothelium may not be the only important factor in the patency of small vessels. A thickened and prominent elastic lamina may also play a role in keeping the lumen open.
从大鼠股静脉切下长度为15毫米的静脉段，置于含乳酸林格液中，4℃冷藏保存长达21天。结果显示，静脉段可保存长达7天，并成功移植给受体。虽然将静脉段保存超过7天也取得了一些成功，但移植到受体后血栓形成率很高。一般认为受损的内皮会导致血栓形成。然而，本研究中的光镜和电镜观察表明，内皮状况可能不是小血管通畅的唯一重要因素。增厚且突出的弹性膜在保持管腔开放方面可能也起作用。
