Pounder D J, Rowland R, Pieterse A S, Freeman R, Hunter R
J Clin Pathol. 1982 Aug;35(8):824-9. doi: 10.1136/jcp.35.8.824.
We studied 14 large bowel resections from patients with a provisional clinical diagnosis of a bleeding vascular lesion of the colon. For the purpose of this study we developed a barium-gelatine vascular injection technique. Six of the 14 cases were proven to be angiodysplasias with an identifiable mucosal vascular ectasia. The pathological findings in these six cases are described. We conclude that angiodysplasia represent a significant cause of lower gastrointestinal haemorrhage in the elderly. It is our opinion that only the mucosa vascular ectasia seen in these cases is histologically diagnostic and that sub-mucosal venous ectasia, while characteristic of angiodysplasia, is non-specific. the differential diagnostic features which will allow the histological distinction of angiodysplasia from other vascular lesions of the colon are discussed.
我们研究了14例初步临床诊断为结肠出血性血管病变患者的大肠切除术。为了本研究的目的,我们开发了一种钡-明胶血管注射技术。14例中有6例被证实为血管发育异常,伴有可识别的黏膜血管扩张。描述了这6例的病理结果。我们得出结论,血管发育异常是老年人下消化道出血的一个重要原因。我们认为,只有这些病例中所见的黏膜血管扩张在组织学上具有诊断意义,而黏膜下静脉扩张虽然是血管发育异常的特征,但并非特异性的。讨论了能够在组织学上区分血管发育异常与结肠其他血管病变的鉴别诊断特征。