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Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog.

作者信息

Montecucchi P C, Gozzini L

出版信息

Int J Pept Protein Res. 1982 Aug;20(2):139-43. doi: 10.1111/j.1399-3011.1982.tb02666.x.

DOI:10.1111/j.1399-3011.1982.tb02666.x
PMID:6981615
Abstract

The secondary structure of sauvagine has been predicted by the statistical method of Chou & Fasman. The results are compared with those obtained by the analysis of the secondary structure of the corticotropin releasing factor. The pattern of helices and beta-turns within these polypeptides is similar. Thus there is an evolutionary relationship in both sequence and secondary structure between these polypeptides, in accordance with their pharmacological properties.

摘要

相似文献

1
Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog.
Int J Pept Protein Res. 1982 Aug;20(2):139-43. doi: 10.1111/j.1399-3011.1982.tb02666.x.
2
Structural homology of corticotropin-releasing factor, sauvagine, and urotensin I: circular dichroism and prediction studies.促肾上腺皮质激素释放因子、大蟾蜍皮肤毒素和尾加压素I的结构同源性:圆二色性和预测研究。
Proc Natl Acad Sci U S A. 1983 Nov;80(22):6770-4. doi: 10.1073/pnas.80.22.6770.
3
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Studies on peptides. CLVII. Synthesis of frog-skin peptide, sauvagine.肽的研究。CLVII。蛙皮肽,蛙皮素的合成。
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Comparison of the biologic actions of corticotropin-releasing factor and sauvagine.促肾上腺皮质激素释放因子与蛙皮素生物活性的比较。
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Characterization of a Pachymedusa dacnicolor-Sauvagine analog as a new high-affinity radioligand for corticotropin-releasing factor receptor studies.将厚皮美杜莎蛙皮素类似物表征为用于促肾上腺皮质激素释放因子受体研究的新型高亲和力放射性配体。
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PH-sauvagine from the skin secretion of Phyllomedusa hypochondrialis: A novel CRF-like peptide with smooth muscle contraction activity.来自亚马逊角蛙皮肤分泌物的PH-蛙皮素:一种具有平滑肌收缩活性的新型促肾上腺皮质激素释放因子样肽。
Toxicon. 2015 Sep 15;104:19-25. doi: 10.1016/j.toxicon.2015.07.012. Epub 2015 Jul 26.

引用本文的文献

1
Corticotropin-releasing factor peptide antagonists: design, characterization and potential clinical relevance.促肾上腺皮质素释放因子肽拮抗剂:设计、表征及潜在临床相关性。
Front Neuroendocrinol. 2014 Apr;35(2):161-70. doi: 10.1016/j.yfrne.2013.10.006. Epub 2013 Nov 20.
2
Structural homology of corticotropin-releasing factor, sauvagine, and urotensin I: circular dichroism and prediction studies.促肾上腺皮质激素释放因子、大蟾蜍皮肤毒素和尾加压素I的结构同源性:圆二色性和预测研究。
Proc Natl Acad Sci U S A. 1983 Nov;80(22):6770-4. doi: 10.1073/pnas.80.22.6770.
3
Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene.
人促肾上腺皮质激素释放因子前体基因的分离与序列分析
EMBO J. 1983;2(5):775-9. doi: 10.1002/j.1460-2075.1983.tb01499.x.
4
Sauvagine-like and corticotropin-releasing factor-like immunoreactivity in the brain of the bullfrog (Rana catesbeiana).
Cell Tissue Res. 1988 Jul;253(1):29-37. doi: 10.1007/BF00221736.