Jakoniuk P, Borowski J
Arch Immunol Ther Exp (Warsz). 1981;29(5):621-6.
The effect of phospholipids extracted from some bacteria and fungi on the response of mice to sheep erythrocytes and E. coli lipopolysaccharide has been studied. The phospholipids from Staphylococcus aureus. Streptococcus faecalis, Bacillus subtilis and Aspergillus fumigatus augmented the humoral immune response to both antigens studied. The phospholipids from Asp. fumigatus, Str. faecalis and Candida albicans stimulated mouse B lymphocyte proliferation in vitro. On the other hand, none of the phospholipids studied could aid ovalbumin to induce delayed hypersensitivity in guinea pigs, and all phospholipids were not mitogenic for mouse T lymphocytes. Phospholipids from Cryptococcus neoformans and Penicillium notatum were without adjuvant activity, and those from C. albicans suppressed the response to sheep erythrocytes.
研究了从某些细菌和真菌中提取的磷脂对小鼠对绵羊红细胞和大肠杆菌脂多糖反应的影响。来自金黄色葡萄球菌、粪肠球菌、枯草芽孢杆菌和烟曲霉的磷脂增强了对所研究的两种抗原的体液免疫反应。来自烟曲霉、粪肠球菌和白色念珠菌的磷脂在体外刺激小鼠B淋巴细胞增殖。另一方面，所研究的磷脂均不能辅助卵清蛋白诱导豚鼠迟发型超敏反应，并且所有磷脂对小鼠T淋巴细胞都没有促有丝分裂作用。新型隐球菌和青霉的磷脂没有佐剂活性，而白色念珠菌的磷脂抑制对绵羊红细胞的反应。
