伤寒沙门氏菌脂多糖和香菇多糖佐剂活性的取向。
The orientation of the adjuvant activities of Salmonella typhosa lipopolysaccharide and lentinan.
作者信息
Dresser D W, Phillips J M
出版信息
Immunology. 1974 Nov;27(5):895-902.
Abstract
By using T cell-deprived mice and appropriate controls it has been shown that the adjuvant activity of LPS on the immune response to different doses of SRBC, tends to be oriented more towards B cells than towards T cells. In contrast, lentinan seems to mediate its adjuvant activity largely through a stimulatory effect on helper T cells.
摘要
通过使用去除T细胞的小鼠和适当的对照，已表明脂多糖（LPS）对不同剂量绵羊红细胞（SRBC）免疫反应的佐剂活性，倾向于更多地作用于B细胞而非T细胞。相比之下，香菇多糖似乎主要通过对辅助性T细胞的刺激作用来介导其佐剂活性。
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本文引用的文献
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Mitogens as probes for immunocyte activation and cellular cooperation.有丝分裂原作为免疫细胞激活和细胞协作的探针。
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Lipopolysaccharide can substitute for helper cells in the antibody response in vitro.脂多糖在体外抗体应答中可替代辅助细胞。
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9
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