妇科癌症盆腔放疗对体液免疫和细胞介导免疫的短期影响。
The short effect of pelvic radiotherapy of gynecological cancers on humoral and cell mediated immunity.
作者信息
Bolla M, Favre M, Bensa J C, Lachet B
出版信息
Biomed Pharmacother. 1982;36(3):139-44.
An analysis of short effect of pelvic irradiation on cellular and humoral immunity was made in 24 patients treated by irradiation alone or a combination of surgery and irradiation for uterine carcinoma, at 2, 6, 12 months after loco-regional therapy. Twelve months later there is a decrease of T lymphocytes (P = 0.01), whereas the B lymphocytes count is normal; the percentage of T and B lymphocytes remains stable, but the lymphocyte response to PHA after 3 days is reduced (p = 0.03). A significant decrease of immunoglobulins G, A and M is observed.
对24例子宫癌患者进行了盆腔照射对细胞免疫和体液免疫短期影响的分析，这些患者接受了单纯放疗或手术与放疗联合治疗，在局部区域治疗后2、6、12个月进行观察。12个月后，T淋巴细胞数量减少（P = 0.01），而B淋巴细胞计数正常；T和B淋巴细胞的百分比保持稳定，但3天后淋巴细胞对PHA的反应降低（P = 0.03）。观察到免疫球蛋白G、A和M显著下降。
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