Davies E G, Levinsky R J, Webster D R, Simmonds H A, Perrett D
Clin Exp Immunol. 1982 Nov;50(2):303-10.
A child with severe combined immunodeficiency due to adenosine deaminase deficiency was treated with thymic hormone (TP1) alone, thymic hormone with red cell transfusions and finally with a combination of these and parenteral deoxycytidine. TP1 alone produced no benefit while the addition of red cell transfusions resulted in only partial immunological restoration despite improvement in clinical and biochemical findings. Deoxycytidine given subcutaneously produced no additional benefit in any of the parameters measured.
一名因腺苷脱氨酶缺乏导致严重联合免疫缺陷的儿童，首先单独接受胸腺激素（TP1）治疗，之后接受胸腺激素与红细胞输注联合治疗，最后接受这些治疗与胃肠外脱氧胞苷联合治疗。单独使用TP1没有效果，而添加红细胞输注尽管临床和生化指标有所改善，但仅导致部分免疫恢复。皮下注射脱氧胞苷在任何测量参数上均未产生额外益处。
