Shamma'a M H, Abu-Samra S, Salameh V, Nassar N T
Int J Epidemiol. 1982 Dec;11(4):406-9. doi: 10.1093/ije/11.4.406.
A comparative seroepidemiologic survey was performed on the prevalence of antibody to HAV (anti-HAV) in 772 subjects in Lebanon. The results show that 97.7% of the adult Lebanese carry anti-HAV in their sera irrespective of geographic or socioeconomic factors, as compared to 38.8% of the adult foreign population. In the paediatric group, the highest prevalence of anti-HAV was encountered at the age of 1-120 days indicating placental transfer of maternal anti-HAV. In the 1-5 year age group there is a sharp drop of anti-HAV to 40%. The anti-HAV of this age group indicates a response to actual infection with HAV. At 12 years the prevalence of anti-HAV is 85%, approaching that of adults. This survey indicates that Lebanon is an endemic area for HAV infection. The age of onset of this infection may be as early as five months, is commonest in the 1-6 year age group and becomes rare again after the age of 12. Finally, fractionation of immunoglobulins of test sera demonstrated that all subjects had their anti-HAV activity in the IgG class, denoting either maternal transfer or old infection and acquired immunity.
对黎巴嫩772名受试者进行了甲型肝炎病毒抗体（抗 - HAV）流行率的比较血清流行病学调查。结果显示，无论地理或社会经济因素如何，97.7%的成年黎巴嫩人血清中携带抗 - HAV，而成人外国人群体的这一比例为38.8%。在儿科组中，抗 - HAV流行率最高出现在1至120天龄时，表明母体抗 - HAV的胎盘转移。在1至5岁年龄组中，抗 - HAV急剧下降至40%。该年龄组的抗 - HAV表明对甲型肝炎病毒实际感染的反应。12岁时，抗 - HAV流行率为85%，接近成年人。这项调查表明黎巴嫩是甲型肝炎病毒感染的流行地区。这种感染的发病年龄可能早在五个月，在1至6岁年龄组中最为常见，12岁以后再次变得罕见。最后，对检测血清的免疫球蛋白进行分级分离表明，所有受试者的抗 - HAV活性均在IgG类别中，这表明要么是母体转移，要么是既往感染及获得性免疫。
