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兔抗小鼠脑血清(RAMBS):在培养中对晚期定向红细胞干细胞(CFU-E)缺乏特异性抑制作用。

Rabbit anti-mouse brain serum (RAMBS): lack of specific inhibition of late committed erythroid stem cells in culture (CFU-E).

作者信息

Adler S S, Kuznetsky R D, Trobaugh F E

出版信息

Blut. 1978 Oct 13;37(4):211-4. doi: 10.1007/BF00996722.

Abstract

Heterologous antisera to mouse brain tissue have activity against mouse pluripotent hemopoietic stem cells (CFU-S), but not against granuloid/macrophage committed precursor cells (CFU-C). In these studies we show that anti-mouse brain serum raised in a rabbit does not possess specific activity in vitro against late committed erythroid stem cells (CFU-E).

摘要

针对小鼠脑组织的异种抗血清对小鼠多能造血干细胞(CFU-S)有活性,但对粒细胞/巨噬细胞定向祖细胞(CFU-C)无活性。在这些研究中,我们表明,在兔体内产生的抗小鼠脑血清在体外对晚期定向红系干细胞(CFU-E)不具有特异性活性。

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