Vetter K, Flury G, Keller P J
Geburtshilfe Frauenheilkd. 1982 Dec;42(12):868-70. doi: 10.1055/s-2008-1037175.
For the prognosis in early pregnancies associated with vaginal bleeding ultra-sonography and bio-chemical methods are prominent today. In a retrospective study of 90 determinations of both chorionic gonadotrophin (HCG) and SP-1 (pregnancy specific protein-1, TGB PS beta G) the prognostic value of these two glyco-proteins synthesized in the trophoblast were compared. Both parameters were reliable for the prognosis of threatened abortion, correlated well with each other and showed excellent statistical results regarding sensitivity, specificity and prognostic value regarding abortion or a chance for continuation of the pregnancy. Both were very efficient. These results show that HCG and SP-1 are equally well suited for the serial evaluation of trophoblast function in early pregnancy. Their value compared to ultra-sonography needs further studies.
对于伴有阴道出血的早期妊娠的预后评估，超声检查和生化方法在当今颇为突出。在一项对90次绒毛膜促性腺激素（HCG）和SP-1（妊娠特异性蛋白-1，TGB PSβG）测定的回顾性研究中，比较了这两种由滋养层合成的糖蛋白的预后价值。这两个参数对于先兆流产的预后评估都是可靠的，它们相互之间相关性良好，并且在流产或妊娠继续可能性的敏感性、特异性和预后价值方面显示出优异的统计结果。两者都非常有效。这些结果表明，HCG和SP-1同样适用于早期妊娠中滋养层功能的系列评估。它们与超声检查相比的价值需要进一步研究。
