[Various immunologic aspects of craniocerebral injuries].

The authors analysed cellular and humoral immunity in 104 patients with different types of craniocerebral injury. It was found that the T system immunity reflects the state of the main mechanisms of the organism's nonspecific resistance while its changes are determined by the level of the brain injury. A marked decrease in the T system values in the acute period of the injury with subsequent rapid restoration reflects an adequate total adaptational reaction of the organism and is characteristic of mild and moderate brain contusion. A normal or high level of cellular immunity values in the acute period of the injury with subsequent profound and prolonged immunodepression is evidence of the absence of this reaction and, consequently, of the deficiency of the nonspecific resistance mechanisms resulting from damage to the brain structures regulating these processes. Such reaction of the immune system was disclosed in severe brain contusion. The periodical character of changes in the organism's immune system after injury may serve as the basis for the therapeutic tactics.