Pishel' Ia V, Grigorova I A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(5):672-5.
A group of 105 patients with contusion foci in the brain was studied for humoral immunity (determinations of IgA, IgG and IgM) in the process of their surgical and conservative treatment, on days 1, 7, 21, 30 and 60. and at 1, 3 and 5 years following contusion foci removal. The decreased levels of IgA, IgG and IgM were revealed at all periods of the traumatic disease. The greatest impairment of immunologic response was observed on day 1 and 7 of disease which was correlated with the severe status of patients, duration and depth of unconsciousness, the severity of general cerebral and focal symptomatology and with attendant bronchopulmonary complications. Immunological methods of investigation in conjunction with clinical ones are of great diagnostic and prognostic value.
对一组105例脑挫伤灶患者在手术和保守治疗过程中，于第1天、第7天、第21天、第30天和第60天以及脑挫伤灶清除后的1年、3年和5年进行了体液免疫（IgA、IgG和IgM测定）研究。在创伤性疾病的所有阶段均发现IgA、IgG和IgM水平降低。在疾病的第1天和第7天观察到免疫反应受损最严重，这与患者的严重状态、昏迷持续时间和深度、全脑和局灶性症状的严重程度以及伴随的支气管肺并发症相关。免疫检查方法与临床检查方法相结合具有很大的诊断和预后价值。
