Ainamo J, Asikainen S, Paloheimo L
J Clin Periodontol. 1982 Jul;9(4):337-45. doi: 10.1111/j.1600-051x.1982.tb02100.x.
During a clinical trial for evaluating the antiplaque effect of two flavoured chlorhexidine rinses, the observation was made that bleeding after gentle massage of the gingival margin occurred more often after chemical than after mechanical oral hygiene measures. In order to ascertain the validity of this unexpected observation, the same dental students participated in a repetition of the trial 18 months later. The results of the two trials indicate that gingival bleeding after gentle massage of the margin with the side of a periodontal probe actually occurs more frequently after rinsing twice daily with a 0.2% aqueous chlorhexidine solution for 1 week than after meticulous mechanical oral hygiene measures during an equally long time period. The average frequency of bleeding, in per cent of all examined gingival units, ranged from 1.3% after mechanical cleaning of the teeth to 5.4% after rinsing with chlorhexidine for 1 week. Neither the frequency of bleeding nor the difference between mechanical and chemical plaque control were considered to be of clinical significance. Further microbiological and histological studies are being conducted in an attempt to clarify the reason for the observed bleeding tendency.
在一项评估两种调味洗必泰漱口水抗牙菌斑效果的临床试验中,观察到在轻柔按摩牙龈边缘后,化学口腔卫生措施后的牙龈出血比机械口腔卫生措施后的更频繁。为了确定这一意外观察结果的有效性,同一批牙科学生在18个月后重复了该试验。两项试验的结果表明,在使用0.2%洗必泰水溶液每日漱口两次、持续1周后,用牙周探针侧面轻柔按摩牙龈边缘后的牙龈出血,实际上比在同样长的时间段内采取细致的机械口腔卫生措施后更频繁。以所有检查的牙龈单位的百分比计算,出血的平均频率在牙齿机械清洁后为1.3%,洗必泰漱口1周后为5.4%。出血频率以及机械和化学菌斑控制之间的差异均未被认为具有临床意义。目前正在进行进一步的微生物学和组织学研究,以试图阐明观察到的出血倾向的原因。