Asikainen S, Paloheimo L, Helminen-Pakkala E, Ainamo J
J Clin Periodontol. 1981 Apr;8(2):139-43. doi: 10.1111/j.1600-051x.1981.tb02353.x.
An experimental study was designed for assessement of whether two recently marketed flavored chlorhexidine mouthrinses, Hibitane Dental (ICI) and Plak-Out (Hawe), have a good plaque-inhibiting effect as the 0.2% aqueous solution of chlorhexidine gluconate. Thirteen dental students used in different sequences each one of the three rinses fro 1 week by rinsing twice daily for 1 min. During the rinsing periods no other oral hygiene measures were allowed. Between two rinsing periods the subjects cleaned their teeth mechanically for 1 week. At the start of each test and control period, the teeth were professionally cleaned with rubber cups and an abrasive paste. At the end of the five 1-week periods the mesial, lingual and facial aspects of the teeth in the right halves of the jaws of each participant were scored for the Plaque Index by the same investigator. After the mechanical cleaning, higher PII scores were recorded than after the chlorhexidine rinses. No difference could be observed among the PII scores after rinsing with the aqueous or the two flavored chlorhexidine solutions.
设计了一项实验研究，以评估两种最近上市的加味洗必泰漱口水——Hibitane Dental（ICI公司）和Plak-Out（哈威公司）——是否具有与0.2%葡萄糖酸洗必泰水溶液一样良好的抑制牙菌斑效果。13名牙科学生按照不同顺序使用这三种漱口水，每种漱口水使用1周，每天漱口两次，每次1分钟。在漱口期间，不允许采取其他口腔卫生措施。在两个漱口期之间，受试者进行1周的机械刷牙。在每个测试和对照期开始时，用橡胶杯和磨砂膏对牙齿进行专业清洁。在五个1周周期结束时，由同一名研究人员对每位参与者下颌右半侧牙齿的近中、舌侧和颊侧进行菌斑指数评分。机械清洁后记录的菌斑指数评分高于洗必泰漱口后。用水溶液或两种加味洗必泰溶液漱口后的菌斑指数评分之间没有差异。
