Malawska B, Gorczyca M, Chojnacka-Wójcik E, Tatarczyńska E
Pol J Pharmacol Pharm. 1982 Nov-Dec;34(5-6):373-82.
N-aminoalkyl derivatives of 2-pyrrolidinone (1-5) and methylene-bis-amino derivatives (7-9) as intermediary products formed during aminoalkylation were described. Compounds 2 and 3, in doses over 30 and 20 mg/kg resp., displayed analgesic properties; compound 3 exerted also a weak anti-inflammatory action (37 mg/kg po) in the carrageenin test.
描述了2-吡咯烷酮的N-氨基烷基衍生物（1-5）和亚甲基双氨基衍生物（7-9）作为氨基烷基化过程中形成的中间产物。化合物2和3，分别以超过30和20mg/kg的剂量显示出镇痛特性；化合物3在角叉菜胶试验中（口服37mg/kg）也表现出微弱的抗炎作用。
