Cheh A M, Skochdopole J, Koski P, Cole L
Science. 1980 Jan 4;207(4426):90-2. doi: 10.1126/science.6985746.
In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.
在饮用水处理过程的实验室模拟中所产生的浓缩水中，通过埃姆斯沙门氏菌试验很容易检测到直接作用的非挥发性诱变剂。已证明这些诱变剂是由氯化过程产生的。用氯胺处理水所产生的诱变活性低于用游离氯处理。用亚硫酸盐对饮用水进行脱氯可大幅降低诱变活性。建议用二氧化硫处理作为一种有效且廉价的方法，以降低饮用水和工业废水的直接作用诱变活性。
