Eifrig D E
South Med J. 1980 Jan;73(1):6-8. doi: 10.1097/00007611-198001000-00006.
The clinical course of implanted intraocular lenses is frequently complicated by the formation of deposits or "precipitates" on the lens surfaces. These lesions are related to the amount of inflammation in the eye, the use of pilocarpine, and the presence of lens cortex in extracapsular procedures. Corticosteroids cause the lesions to diminish or disappear. Similar lesions seen in the course of lens implantation in laboratory animals are found on histologic examination to be accumulations of inflammatory cells. In the chronic state the cells are macrophages, epithelioid cells, and giant cells, accompanied in the early stages by acute inflammatory leukocytes. The relationships between these cells, inflammation, the presence of the foreign body, and the chemistry of methacrylate are difficult to sort out.
人工晶状体的临床过程常常因晶状体表面形成沉积物或“沉淀物”而变得复杂。这些病变与眼内炎症的程度、毛果芸香碱的使用以及囊外手术中晶状体皮质的存在有关。皮质类固醇可使这些病变减轻或消失。在实验室动物晶状体植入过程中观察到的类似病变，经组织学检查发现是炎症细胞的聚集。在慢性状态下，这些细胞是巨噬细胞、上皮样细胞和巨细胞，早期伴有急性炎症白细胞。这些细胞、炎症、异物的存在与甲基丙烯酸酯化学性质之间的关系很难理清。
