Fischer R G
J Fam Pract. 1980 Mar;10(3):427-35.
Simplifying drug regimens is one method of improving patient compliance. Medications originally administered several times a day are now reported to maintain 24-hour effectiveness on once-daily administration. In many cases this technique of administration results in the use of less expensive medication, an improvement in compliance, and even decreased side effects. All patients may not be controlled or tolerate increased intervals between drug doses. Interpatient variation dictates that physicians closely monitor their patients when prescribing new or unapproved regimens of drug therapy.
简化给药方案是提高患者依从性的一种方法。据报道，原本一天给药几次的药物现在每日给药一次就能维持24小时的疗效。在许多情况下，这种给药技术会带来使用更便宜药物的结果，提高了依从性，甚至减少了副作用。并非所有患者都能耐受药物剂量间隔时间的增加。个体差异决定了医生在开新的或未经验证的药物治疗方案时要密切监测患者。
