Stewart W M
Dermatologica. 1980;160(4):217-35.
This comparison of the two diseases--pemphigus and pemphigoid--aimed particularly on points of actual interest. Are thus reviewed: (1) the research on the influence of racial or genetic factors in pemphigus vulgaris; (2) the striking differences between the immunological criteria of the two; (3) the clinical polymorphism of pemphigus: besides pemphigus superficialis, non-bullous forms, usually milder, of various types: herpetiformis, circinate ... are now being described; (4) the importance in all cases of eosinophilic spongiosis; (5) the clinical monomorphism of classical bullous pemphigus; on the contrary, the differences, both from clinical and prognostic points of view, in localized bullous pemphigoid (from the benign mucocutaneous form to the severe scarring disease) and in bullous pemphigoid of children; (3) the cases of genuine pemphigus induced by drugs (D-penicillamine, rifampicine) and the problem of the pemphigus-like antibodies; (7) bullous pemphigoid, UV light and practolol; (8) the outstanding association of two major immune diseases, pemphigus vulgaris, myasthenia and thymoma; (9) the mixed bullous dermatoses: pemphigus vulgaris and dermatosis herpetiformis (to separate from herpetiform pemphigus), bullous pemphigoid and dermatosis herpetiformis (bringing up the unsolved problem of mixed or intermediate forms of the two diseases), bullous pemphigoid and pemphigus vulgaris, exceptionally seen, and (10) some news on therapy.
对天疱疮和类天疱疮这两种疾病的比较尤其关注实际感兴趣的要点。现对以下内容进行综述:(1)寻常型天疱疮种族或遗传因素影响的研究;(2)两者免疫学标准的显著差异;(3)天疱疮的临床多态性:除浅表性天疱疮外,还描述了各种通常较轻的非大疱性类型,如疱疹样、环状……;(4)嗜酸性海绵形成在所有病例中的重要性;(5)经典大疱性天疱疮的临床单态性;相反,局限性大疱性类天疱疮(从良性黏膜皮肤型到严重瘢痕性疾病)和儿童大疱性类天疱疮在临床和预后方面的差异;(3)药物(D-青霉胺、利福平)诱发的真正天疱疮病例及天疱疮样抗体问题;(7)大疱性类天疱疮、紫外线和心得宁;(8)两种主要免疫疾病寻常型天疱疮、重症肌无力和胸腺瘤的显著关联;(9)混合性大疱性皮肤病:寻常型天疱疮和疱疹样皮炎(与疱疹样天疱疮相鉴别)、大疱性类天疱疮和疱疹样皮炎(提出两种疾病混合或中间形式的未解决问题)、大疱性类天疱疮和寻常型天疱疮(罕见),以及(10)一些治疗方面的新消息。