Quinn R W
South Med J. 1980 Mar;73(3):288-96. doi: 10.1097/00007611-198003000-00007.
Incidence and prevalence of hemolytic and group A streptococci were determined for 3,479 school children in Nashville, Tennessee from 1953-1954 through 1973-1974 inclusive. Of 53,827 throat cultures, 17.98% were positive for hemolytic streptococci and 12.87% for group A; 26.19% group A strains were typable. Types 6, 1, 12, 4, 5, and 3 were the most frequently isolated. Percentages of children with at least one positive culture for both hemolytic (H) and group A streptococci (A) were highest in 1953-1954 (H--79.3%, A--71.0%); 1963-1964 (H--83.5%, A--74.6%); 1969-1970 (H--74.6%, A--65.0%); and 1973-1974 (H--83.1%, A--71.1%) and highest by month in February, declining erratically until the summer. Some children acquired type-specific antibodies in the absence of streptococcal disease. There was a significant increase in positivity rates for hemolytic and group A streptococci from ages 5 to 7 through age groups 6 to 8 and 7 to 9 and a slow decline in the older age groups. Race did not appear to be an important factor in determining positivity rates; rates were significantly higher among children from low socioeconomic areas regardless of whether they were black or white.
1953年至1954年至1973年至1974年（含）期间，对田纳西州纳什维尔市的3479名学童进行了溶血性链球菌和A组链球菌的发病率及患病率测定。在53827份咽拭子培养物中，17.98%的溶血性链球菌呈阳性，A组链球菌为12.87%；26.19%的A组菌株可分型。6型、1型、12型、4型、5型和3型是最常分离出的类型。1953年至1954年（溶血性链球菌——79.3%，A组链球菌——71.0%）、1963年至1964年（溶血性链球菌——83.5%，A组链球菌——74.6%）、1969年至1970年（溶血性链球菌——74.6%，A组链球菌——65.0%）以及1973年至1974年（溶血性链球菌——83.1%，A组链球菌——71.1%）中，至少有一次溶血性（H）和A组链球菌（A）培养阳性的儿童百分比最高；按月来看，2月份最高，之后不规则下降直至夏季。一些儿童在没有链球菌病的情况下获得了型特异性抗体。从5至7岁年龄组到6至8岁和7至9岁年龄组，溶血性和A组链球菌的阳性率显著上升，而在年龄较大的年龄组中则缓慢下降。种族似乎不是决定阳性率的重要因素；无论黑人还是白人，来自社会经济地位低的地区的儿童阳性率显著更高。
