Ishiguro N, Makino S, Sato G, Hashimoto K
Am J Vet Res. 1980 Jan;41(1):46-50.
A total of 84 Salmonella isolates of ten serovars from swine in Japan were tested for antibiotic susceptibility and detection of R plasmids. Of these, 58 (69.0%) were resistant to one or more antibiotic(s) such as tetracycline, streptomycin, sulfadimethoxine, and chloramphenicol; and 38 (65.5%) of the 58 resistance isolates (mainly Salmonella typhimurium isolates) had conjugative R plasmids. Among the 38 conjugative R plasmids, 36 thermosensitive R plasmids carrying tetracycline resistance were Fi- (no fertility inhibition) and belonged to incompatibility group Hl, whereas the R plasmids carrying streptomycin and sulfadimethoxine resistances coexisted in the same host, were Fi+, and were also compatible with the reference R plasmids tested. The epidemiologic significance of R plasmids derived from Salmonella isolates from swine is discussed.
对从日本猪身上分离出的10个血清型的84株沙门氏菌进行了抗生素敏感性测试和R质粒检测。其中，58株（69.0%）对四环素、链霉素、磺胺二甲氧嘧啶和氯霉素等一种或多种抗生素耐药；58株耐药菌株（主要是鼠伤寒沙门氏菌菌株）中的38株（65.5%）具有接合性R质粒。在38个接合性R质粒中，36个携带四环素抗性的热敏R质粒为Fi -（无育性抑制），属于不相容群Hl，而携带链霉素和磺胺二甲氧嘧啶抗性的R质粒共存于同一宿主中，为Fi +，并且也与所测试的参考R质粒相容。文中讨论了源自猪沙门氏菌分离株的R质粒的流行病学意义。
