Miltenburger H G, David P
Dev Biol Stand. 1980;46:183-6.
The production of insect pathogenic viruses for the use in integrated pest control is presently done in vivo in populations of their natural hosts. However, efforts are made in several laboratories to produce some of these baculoviruses in insect cell cultures. The mass production of the viruses in vitro depends on a technology for the mass production of cells. Data are presented for the production of up to 10(10) insect cells per logarithmic growth phase in a continuously running fermenter culture at volumes of 9-10 litres.
用于害虫综合防治的昆虫致病病毒目前是在其自然宿主种群中进行体内生产的。然而，一些实验室正在努力在昆虫细胞培养物中生产其中一些杆状病毒。病毒的体外大规模生产取决于细胞大规模生产技术。本文给出了在9 - 10升体积的连续运行发酵罐培养中，每个对数生长期可生产多达10¹⁰个昆虫细胞的数据。
