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1%洗必泰凝胶在反斜面龈黏膜瓣手术后愈合阶段的效果。

Effects of a 1% chlorhexidine gel during the healing phase after inverse bevel mucogingival flap surgery.

作者信息

Bakaéen G S, Strahan J D

出版信息

J Clin Periodontol. 1980 Feb;7(1):20-5. doi: 10.1111/j.1600-051x.1980.tb01945.x.

Abstract

A split-mouth double-blind trial was designed to compare the effects of chlorhexidine and placebo gels during the healing phase following mucogingival flap surgery. Fifteen patients were treated with 30 inverse bevel flap procedures, one on each side of the maxilla, with an interval of 4 weeks between each procedure. Gel was applied to the gums using a toothbrush once daily. Comparison of results revealed no significant differences in Plaque Index, Gingival Index, crevicular fluid or depth of pockets. More pain and swelling were recorded on the side treated with placebo gel, and more patients indicated that they preferred the chlorhexidine gel. The results were comparable to previous investigations using penicillin and suggest that, because of the reduced pain and swelling, chlorhexidine gel may be a suitable alternative to penicillin after periodontal flap surgery.

摘要

一项双盲、交叉对照试验旨在比较洗必泰凝胶和安慰剂凝胶在龈黏膜瓣手术后愈合阶段的效果。15名患者接受了30次反向斜面瓣手术,每侧上颌各进行一次,每次手术间隔4周。每天使用牙刷将凝胶涂抹于牙龈。结果比较显示,菌斑指数、牙龈指数、龈沟液或牙周袋深度方面无显著差异。使用安慰剂凝胶治疗的一侧记录到更多疼痛和肿胀,更多患者表示他们更喜欢洗必泰凝胶。结果与之前使用青霉素的研究相当,表明由于疼痛和肿胀减轻,洗必泰凝胶可能是牙周瓣手术后青霉素的合适替代品。

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