Luby J P, Murphy F K, Gilliam J N, Kang C Y, Frank R
Am J Trop Med Hyg. 1980 Mar;29(2):265-8. doi: 10.4269/ajtmh.1980.29.265.
Patients with St. Louis encephalitis may have urinary tract symptoms when they develop manifestations related to involvement of the central nervous system. During 1976, 12 patients with St. Louis encephalitis were studied for the presence of antigenuria, and compared to controls. Although virus isolation attempts were negative indirect immunofluorescence, electron microscopy, and immune electron microscopy demonstrated the presence of viral antigen in urine. Further study of antigenuria in St. Louis encephalitis is needed to delineate the pathophysiology of the lower urinary tract symptoms and to determine whether this phenomenon might furnish the basis for a rapid diagnostic test for the disease.
患有圣路易斯脑炎的患者在出现与中枢神经系统受累相关的表现时，可能会有泌尿系统症状。1976年期间，对12例圣路易斯脑炎患者进行了尿中抗原检测，并与对照组进行了比较。尽管病毒分离尝试结果为阴性，但间接免疫荧光、电子显微镜和免疫电子显微镜检查均显示尿液中存在病毒抗原。需要对圣路易斯脑炎患者的尿中抗原进行进一步研究，以阐明下尿路症状的病理生理学，并确定这种现象是否可能为该疾病的快速诊断测试提供依据。
