Friedman A, Fleisher G
Clin Pediatr (Phila). 1980 Jun;19(6):395-7. doi: 10.1177/000992288001900603.
Our series of children with meningitis shows an increase in the frequency of isolation of Hemophilus influenzae type B. This increase is most marked among children between one and two months of age. Since H. influenzae was found in five of the seven children between thirty and sixty days of age, we recommend the use of chloramphenicol for the initial treatment of bacterial meningitis after the first month of life. Additionally, our mortality data suggest that early diagnosis and intensive supportive therapy can contribute to a further decrease in the fatality rate of this disease.
我们的一系列脑膜炎患儿显示出B型流感嗜血杆菌分离频率增加。这种增加在1至2个月大的儿童中最为明显。由于在30至60日龄的7名儿童中有5名发现了流感嗜血杆菌，我们建议在出生后第一个月后使用氯霉素进行细菌性脑膜炎的初始治疗。此外，我们的死亡率数据表明，早期诊断和强化支持治疗有助于进一步降低这种疾病的死亡率。
