[Insulin secretion after surgery: measurements after abdominal operations].

The study includes measurements of glucose and insulin in 30 patients after surgical trauma. The times of measurements were between the 2nd and 6th, 6th and 10th, and 10th and 21st postoperative days. An intravenous glucose load (1 g/kg body weight/60 min) was used. For the exact measurement of secretion of the islet cells we also determined insulin and glucose in portal venous blood. The following conclusions were made: (1) Measurements of insulin in the peripheral venous blood has no exact correlation to insulin secretion in the postoperative period. The insulin concentration in the portal vein blood after a glucose load shows significant variations to the insulin concentration in the cubital vein blood. (2) A greater surgical trauma (abdominal operation) causes a disorder of glucose utilization in the first postoperative week. (3) The insulin secretion after intravenous glucose load is significantly diminished during the first operative week.