钚-241在大鼠肋骨中的沉积与再分布。

241Plutonium deposition and redistribution in the rat rib.

作者信息

Priest N D, Giannola S J

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1980 Mar;37(3):281-98. doi: 10.1080/09553008014550331.

Abstract

Using the techniques of 241plutonium autoradiography and plutonium alpha-autoradiography the distribution of intravenously injected plutonium in the rat rib has been investigated, at times up to 4 months after injection. The results showed that at some time plutonium either became buried in the bone cortex or was resorbed. Plutonium which was resorbed was found in osteoclasts and macrophages. Subsequently, much of the resorbed plutonium was redeposited. The dosimetric implications of the results are discussed.

摘要

利用钚-241放射自显影技术和钚α放射自显影技术，对大鼠肋骨中静脉注射钚后的分布情况进行了研究，观察时间长达注射后4个月。结果表明，钚在某些时候要么埋入骨皮质，要么被吸收。被吸收的钚存在于破骨细胞和巨噬细胞中。随后，大部分被吸收的钚会重新沉积。文中讨论了这些结果在剂量学方面的意义。