直径为1.0纳米的二氧化钚-238颗粒与大鼠肺液的反应。
The reactions of 1.0 nanometre diameter plutonium-238 dioxide particles with rat lung fluid.
作者信息
Cooper J R, Stradling G N, Smith H, Breadmore S E
出版信息
Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Nov;36(5):453-66. doi: 10.1080/09553007914551251.
The reactions of 1.0 nm particles of plutonium-238 dioxide with rat lung fluid have been studied both in vivo and in vitro. In both cases two products have been identified, (i) plutonium-labelled pulmonary surfactant and (ii) a heterogeneous plutonium-labelled material isolated by column chromatography. The formation of plutonium-labelled pulmonary surfactant results in the rapid translocation of plutonium from lungs to blood and in a high urinary excretion relative to administered plutonium citrate.
已在体内和体外研究了二氧化钚-238的1.0纳米颗粒与大鼠肺液的反应。在这两种情况下，均鉴定出两种产物：(i) 钚标记的肺表面活性剂和 (ii) 通过柱色谱法分离出的一种异质钚标记物质。钚标记的肺表面活性剂的形成导致钚从肺快速转运至血液，并相对于给予的柠檬酸钚有较高的尿排泄量。
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