Noble M J, Magnusson M O, Stowe N T, Novick A C, Straffon R A
Invest Urol. 1980 May;17(6):503-5.
Dog kidneys subjected to a period of warm ischemia followed by either simple cold storage or hypothermic pulsatile perfusion were autotransplanted 24 hr after harvesting, and a contralateral nephrectomy was performed at the same time. Renal function was comparable with both techniques, and all dogs survived. When kidneys were subjected to 30 min of warm ischemia followed by one of the two preservation methods, renal function was again comparable and 50 per cent of the animals in each group survived. We conclude, therefore, that for 24 hr of canine renal preservation, cold storage is as effective as pulsatile perfusion even when the kidney has been initially subjected to 30 min of warm ischemia.
对狗的肾脏进行一段时间的热缺血，随后分别采用单纯冷藏或低温脉动灌注，在摘取肾脏24小时后进行自体移植，同时施行对侧肾切除术。两种技术的肾功能相当，所有狗均存活。当肾脏经历30分钟热缺血后采用两种保存方法之一时，肾功能再次相当，每组50%的动物存活。因此，我们得出结论，对于犬肾保存24小时而言，即使肾脏最初经历了30分钟热缺血，冷藏与脉动灌注的效果一样好。
